This website has been designed to visualize GPCR interaction networks. Four types of interaction networks are available: HetNet, NonHetNet, RTK, and Parkinson. In the HetNet network, each receptor represents a node, and every connecting line indicates that the two receptors interact according to the consulted literature. In the NonHetNet network, each dotted line denotes a lack of interaction between the connected receptors. The RTK network displays interactions specific to receptor tyrosine kinases (RTKs), highlighting their distinct pathways and connections. The Parkinson network is analogous to the HetNet, but highlights the receptors related to Parkinson's disease, with nodes colored according to their relevance in Parkinson's research. The size of each node reflects the number of connections it has, and networks can be chosen using the buttons at the top center of the page.

Interaction and non-interaction data for a specific receptor can be explored in two ways:

• By using the search box located in the top-left panel. The search is equipped with an autocomplete feature, so only part of the receptor name is needed to locate the desired receptor. Receptor names follow the UniProt nomenclature. For reference, consult the UniProt website.
• By clicking directly on the receptor within the network visualization.

The interface includes three additional panels. The top-left panel presents a color map linking receptor families to node colors within the network.

The top-right panel, which appears only when a target receptor is selected, provides information about the corresponding subnetwork. For each receptor within that subnetwork, bibliographic references are listed to support the reported interactions or non-interactions with the selected receptor.

Network URLs are shareable. After selecting a network and a receptor, the URL can be copied and shared, enabling others to access the same view and configuration.

The bottom-right corner displays topological properties of the currently selected network. The network data can also be downloaded as a tab-separated .txt file.